Many histamine intolerance sufferers are initially unaware that many painkillers are also unsuitable. This is because most painkillers contain what are known as histamine releasers. These are substances that release histamine, which is naturally present in mast cells. DAO blockers can also be a problem. DAO is the main degradation pathway in the intestine. Certain substances can inhibit DAO enzyme activity by their presence in the body.

 

As you can see, the question "Which painkillers for histamine intolerance?" is not quite so easy to answer. For one thing, it must first be checked whether the active ingredient of the medication is tolerated. Once this has been done and a tolerable active ingredient has been found, it must be checked which excipients are contained in the medication. This is because a tolerated active ingredient does not necessarily mean that the entire painkiller is tolerated.

Compatible active ingredients:

Thus, in the case of histamine intolerance, the over-the-counter agents paracetamol and ibuprofen are recommended. Among prescription painkillers, almost all of them show a histamine effect except for tilidine.

Incompatible active ingredients in painkillers:

 

- Acetylsalicylic acid

- Diclofenac

- Naproxen

- Metamizole / Novaminsulfone

- Indomethacin

- Morphine

 

But beware!

Consideration must be given not only to the active ingredients, but also to the excipients, which may also be contained in the respective drug. This means that even if the active ingredient, for example ibuprofen as mentioned above, is tolerated, excipients may mean that the drug as a whole is not tolerated.

The following excipients are incompatible with histamine intolerance:

- Alginic acid: in tablets as a binder 

- Benzoic acid: in liquids as a preservative

- Citric acid: in liquids for PH value adjustment

- Gelatin: in the shell of capsules as a binder

- Potassium sorbate: in liquids as a preservative

- Parabens: in liquids as preservatives

 

Here are some examples of tolerated pain relievers for histamine intolerance:

Painkillers with paracetamol:

Painkillers with ibuprofen:

References:

https://www.histaminintoleranz.ch/de/

histaminosis_dao-abbaustoerung.html

https://www.whatsinmymeds.de/allgemein/

https://www.mein-allergie-portal.com/allergie-wiki/

101-histamineliberators.html




Note: The information on this page has been carefully researched, but we do not guarantee its completeness or accuracy. If you have any health problems, please consult your doctor.
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Painkillers for histamine intolerance

Many people with histamine intolerance are initially unaware that many painkillers are also unsuitable. This is because most painkillers contain so-called histamine liberators. These are substances that release the body's own histamine in mast cells. DAO blockers can also be a problem. DAO is the main degradation pathway in the intestine. Certain substances can inhibit DAO enzyme activity by their presence in the body. As you can see, the question "Which painkillers for histamine intolerance?" is not so easy to answer. On the one hand, it is necessary to check whether the active ingredient is tolerated. On the other hand, it is also necessary to check which excipients are contained in the medication.